GATHER THE DATA
Patient photo
Patient history and presentation
  • 45-year-old Caucasian female
  • Loss of sensation to light touch in feet
  • Bilateral weakness in arms and legs that has progressed over the last 3 months
  • Loss of balance
  • Reduced deep tendon reflexes in all extremities
  • No family history of neuromuscular disorders
NEXT...DIG DEEPER
WHICH LABS AND TESTS
WOULD YOU ORDER?
(Select all that apply)
  • Electromyography
  • Nerve conduction studies
  • Quantitative sensory testing
  • Autonomic testing
  • Lumbar puncture
  • Biopsy: Nerve, skin, and/or fat pad
  • Genetic testing
ENTER SELECTIONS
Test Results

Thank you for your selections. The results for the tests and labs the case physician selected are below.

  • Labs: Normal glucose, renal, liver, and thyroid function
  • Electromyography with nerve conduction study: Reduced conduction velocity, prolonged distal motor latency, distance dependent reduction of compound motor action potential amplitude, prolonged F-wave latency
  • Lumbar puncture: Elevated protein in cerebrospinal fluid (CSF)
  • Sural nerve biopsy: Macrophage-associated demyelination, onion bulb formation, Congo red negative
  • Genetic test: No TTR gene mutations identified
MAKE THE CALL Which is the most likely diagnosis?
(Choose one)
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